Legal contracts and litigation documents common to the American legal system were encoded in the eXtensible Markup Language (XML). XML also represents rules about the contracts and litigation procedure. In addition to an expert system tool that allows one to make inferences with that engine, a Graphical User Interface (GUI) generates the XML representing the rules. A rulebase is developed by marking up examples of the XML to be interpreted and the XML to be generated, analogously to Query By Example. (...) This article provides a broader context of the synergy between XML and artificial intelligence by including discussions of: (1) the role of Artificial Intelligence in handling routine litigation; (2) how the use of XML enables legal expert systems to get their `input' without the user having to enter the same information again for the expert system;(3) the advantages of XML markup over other forms of markup for documents; (4) the relationship between XML and ontologies; (5) other projects using XML with rules or legal affairs. (shrink)

One of the principal characteristics of contemporary inquiry is the rediscovery of human consciousness. This book attempts to develop that experience and continue the insight of the legendary Hermes Trismegistos that 'thought is God the Father.' The author invites the reader to attend to his own act of thinking.

Though usually Edmund Burke is identified as the first to articulate the principles of a modern conservative political tradition, arguably he was preceded by a Scotsman who is better known for espousing a brilliant concept of skepticism. As Laurence Bongie notes, "David Hume was undoubtedly the eighteenth-century British writer whose works were most widely known and acclaimed on the Continent during the later Enlightenment period. Hume's impact in France] was of undeniable importance, greater even for a time than the (...) related influence of Burke, although it represents a contribution to French counter-revolutionary thought which, unlike that of Burke, has been almost totally ignored by historians to this day." The bulk of Bongie's work consists of the writings of French readers of Hume who were confronted, first, by the ideology of human perfection and, finally, by the actual terrors of the French Revolution. Offered in French in the original edition of David Hume published by Oxford University Press in 1965, these vitally important writings have been translated by the author into English for the Liberty Fund second edition. In his foreword, Donald Livingston observes that "If conservatism is taken to be an intellectual critique of the first attempt at modern total revolution, then the first such event was not the French but the Puritan revolution, and the first systematic critique of this sort of act was given by Hume." Laurence L. Bongie is Professor Emeritus of French at the University of British Columbia. Donald Livingston is Professor of Philosophy at Emory University. Please note: This title is available as an ebook for purchase on Amazon, Barnes and Noble, and iTunes. (shrink)

Some of the authors of the essays on Chinese philosophers prefer the pin yin system of romanization for Chinese names and words, while others prefer the Wade‐Giles system. Given that both systems are in wide use today, important names and words are given in both their pin yin and Wade‐Giles formulations. The author's preference is printed first, followed by the alternative romanization within brackets.

The processes underwriting the acquisition of culture remain unclear. How are shared habits, norms, and expectations learned and maintained with precision and reliability across large-scale sociocultural ensembles? Is there a unifying account of the mechanisms involved in the acquisition of culture? Notions such as “shared expectations,” the “selective patterning of attention and behaviour,” “cultural evolution,” “cultural inheritance,” and “implicit learning” are the main candidates to underpin a unifying account of cognition and the acquisition of culture; however, their interactions require greater (...) specification and clarification. In this article, we integrate these candidates using the variational (free-energy) approach to human cognition and culture in theoretical neuroscience. We describe the construction by humans of social niches that afford epistemic resources called cultural affordances. We argue that human agents learn the shared habits, norms, and expectations of their culture through immersive participation in patterned cultural practices that selectively pattern attention and behaviour. We call this process “thinking through other minds” (TTOM) – in effect, the process of inferring other agents’ expectations about the world and how to behave in social context. We argue that for humans, information from and about other people's expectations constitutes the primary domain of statistical regularities that humans leverage to predict and organize behaviour. The integrative model we offer has implications that can advance theories of cognition, enculturation, adaptation, and psychopathology. Crucially, this formal (variational) treatment seeks to resolve key debates in current cognitive science, such as the distinction between internalist and externalist accounts of theory of mind abilities and the more fundamental distinction between dynamical and representational accounts of enactivism. (shrink)

Σε μια ανασκόπηση των ιπποκρατικών μελετών, αξίζει να σημειωθούν οι νέες αναγνώσεις, διότι πρόκειται για μια πρώτης τάξεως πηγή με συνοχή στη χρονολογία (μέσα 5ου - μέσα 4ου αι. π.Χ.). Ωστόσο, ο κατάλογος των αγγείων που αναφέρονται στο Corpus αυτό δεν είναι ομοιογενής, εφόσον τα σχήματα τους ποικίλλουν ανάλογα με τη θεραπευτική ή τη διδακτική τους χρήση. Τα χρηστικά αγγεία, μεγαλύτερα στον αριθμό, ενδιαφέρουν κυρίως τους γιατρούς όταν πρόκειται για καθαρά θεραπευτική χρήση, πράγμα που εξηγεί τη σπανιότητα των αγγείων πόσεως (...) και τη μεγάλη αφθονία των αγγείων που χρησίμευαν για την ατμοθεραπεία, χύτρες αλλά και οικιακά σκεύη διαφόρων ειδών, με μεταλλαγμένη συχνά χρήση. Αλλά ο εμπειρισμός αυτός συνοδεύεται με αυστηρότητα (βλ. την εμμονή στα «νέα» αγγεία), όπως αποδεικνύει η προσφυγή στην αναλογική μέθοδο, προορισμένη να διαφωτίζει φαινόμενα αόρατα : τα αγγεία χρησιμεύουν κυρίως για να δηλώσουν προβλήματα σχετικά με το χώρο και την κίνηση. (shrink)

The contributions in this volume make an important effort to resurrect a rather old fashioned form of foundationalism. They defend the position that there are some beliefs that are justified, and are not themselves justified by any further beliefs. This epistemic foundationalism has been the subject of rigorous attack by a wide range of theorists in recent years, leading to the impression that foundationalism is a thing of the past. DePaul argues that it is precisely the volume and virulence of (...) the assaults which points directly to the strength and coherence of the position. (shrink)

Book reviewed in this article: Long Term Care: Principles, Programs and Policies. By Rosalie A. Kane and Robert L. Kane. Long Term Health Care: providing a Spectrum of Services to the Aged. By Philip W. Brickner, Anthony J. Lechich, Roberta Lipsman, and Linda K. scharer.

Book reviewed in this article: Long Term Care: Principles, Programs and Policies. By Rosalie A. Kane and Robert L. Kane. Long Term Health Care: providing a Spectrum of Services to the Aged. By Philip W. Brickner, Anthony J. Lechich, Roberta Lipsman, and Linda K. scharer.

The target article “Thinking Through Other Minds” (TTOM) offered an account of the distinctively human capacity to acquire cultural knowledge, norms, and practices. To this end, we leveraged recent ideas from theoretical neurobiology to understand the human mind in social and cultural contexts. Our aim was bothsynthetic– building an integrative model adequate to account for key features of cultural learning and adaptation; andprescriptive– showing how the tools developed to explain brain dynamics can be applied to the emergence of social and (...) cultural ecologies of mind. In this reply to commentators, we address key issues, including: (1) refining the concept of culture to show how TTOM and the free-energy principle (FEP) can capture essential elements of human adaptation and functioning; (2) addressing cognition as an embodied, enactive, affective process involving cultural affordances; (3) clarifying the significance of the FEP formalism related to entropy minimization, Bayesian inference, Markov blankets, and enactivist views; (4) developing empirical tests and applications of the TTOM model; (5) incorporating cultural diversity and context at the level of intra-cultural variation, individual differences, and the transition to digital niches; and (6) considering some implications for psychiatry. The commentators’ critiques and suggestions point to useful refinements and applications of the model. In ongoing collaborations, we are exploring how to augment the theory with affective valence, take into account individual differences and historicity, and apply the model to specific domains including epistemic bias. (shrink)

On February 3, 2010, a “Letter of Concern from Bioethicists,” organized by fetaldex.org, was sent to report suspected violations of the ethics of human subjects research in the off-label use of dexamethasone during pregnancy by Dr. Maria New. Copies of this letter were submitted to the FDA Office of Pediatric Therapeutics, the Department of Health and Human Services (DHHS) Office for Human Research Protections, and three universities where Dr. New has held or holds appointments. We provide a critical appraisal of (...) the Letter of Concern and show that it makes false claims, misrepresents scientific publications and websites, fails to meet standards of evidence-based reasoning, makes undocumented claims, treats as settled matters what are, instead, ongoing controversies, offers “mere opinion” as a substitute for argument, and makes contradictory claims. The Letter of Concern is a case study in unethical transgressive bioethics. We call on fetaldex.org to withdraw the letter and for co-signatories to withdraw their approval of it. (shrink)

Descartes a entrepris de détruire la pratique aristotélicienne de la philosophie : à son savoir seulement probable, les Regulae, puis les Essais opposent une science certaine d'objets clairs et distincts. Mais cette instauration concerne aussi, peut-être même d'abord, l'idéal pratique qu'Aristote ne cesse de viser dans les sciences théorétiques : le sage parvient à la félicité par l'exercice même d'une connaissance si parfaite qu'elle imite celle du dieu, qui pense sa pensée en acte et éternellement. Descartes met décidément en crise (...) la félicité par la contemplation, dont la pensée médiévale avait hérité d'Aristote. Pourtant, une autre figure de la félicité se dégage tout aussi indiscutablement de l'entreprise cartésienne : la méthode, la certitude scientifique qu'elle permet et les principes métaphysiques qui assurent l'une et l'autre restent, à chaque moment, solidaires d'une attitude et d'une ambition proprement morales - la volonté infinie aboutit à la générosité, où la considération du bon usage de notre libre-arbitre permet le - contentement de soi-même -. Ainsi la philosophie atteint-elle, pour Descartes aussi, à une félicité. Mais à une félicité volontaire et non plus contemplative. On tentera donc d'abord de mesurer, dans différents champs de la philosophie cartésienne, l'impact de la certitude jusque sur les questions d'éthique ; ensuite, de souligner la référence constante, quoique souvent implicite, de Descartes à la félicité telle qu'Aristote la visait ; enfin, de suivre leur dialogue au fil conducteur de leurs versions divergentes, mais complices, de l'admiratio et du thaumazein. (shrink)

TOT states may be viewed as a temporary and reversible microamnesia. We investigated the effects of lorazepam on TOT states in response to general knowledge questions. The lorazepam participants produced more commission errors and more TOTs following commission errors than the placebo participants . The resolution of the TOTs was unimpaired by the drug. Neither feeling-of-knowing accuracy nor recognition were affected by lorazepam. The higher level of incorrect recalls produced by lorazepam participants may be due to the fact that they (...) were more frequently temporarily unable to access a known item. For some of these items, the awareness of the retrieval failure resulted in a commission TOT . The resolution of the TOT conflict is discussed in the light of the anxiolytic and anticonflict effects of lorazepam. The data are discussed in terms of contemporary theories of TOTs and the effects that benzodiazepines have on semantic memory. (shrink)

La recherche des causes apparaît à la fois comme un impérieux besoin de l'esprit humain et, sous la plume de nombreux acteurs du développement historique des connaissances, comme un obstacle. L'examen comparé des tendances majeures du raisonnement commun et des théories scientifiques actuellement enseignées fait apparaître des écarts importants quant à leur statut du point de vue de la causalité. " Donc ", " alors ", " ensuite " : ce trio de vocables résume la question que posent la part (...) de l'implication logique et celle des relations temporelles entre cause et effet. La causalité au sens où les physiciens l'entendent se distingue ainsi du lien qu'une relation pose entre grandeurs prises au même instant. Le débat rejoint ainsi la notion de fonction - et son nécessaire développement vers les fonctions de plusieurs variables - ainsi que celle des associations probabilistes entre grandeurs. Cet ouvrage invite à un examen croisé de la manière dont ce thème est abordé dans différentes disciplines (mathématiques, sciences physiques, biologie, histoire-géographie), sous le double regard de la didactique et de l'épistémologie. (shrink)

While it has often been assumed that, in humans, synonymous mutations would have no effect on fitness, let alone cause disease, this position has been questioned over the last decade. There is now considerable evidence that such mutations can, for example, disrupt splicing and interfere with miRNA binding. Two recent publications suggest involvement of additional mechanisms: modification of protein abundance most probably mediated by alteration in mRNA stability1 and modification of protein structure and activity,2 probably mediated by induction of translational (...) pausing. These case histories put a further nail into the coffin of the assumption that synonymous mutations must be neutral. BioEssays 29:515–519, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

Η Ιπποκρατική Συλλογή παρέχει δύο τύπους πληροφοριών σχετικά με τα αγγεία : άλλοτε συμπληρώνει τις πληροφορίες που υπάρχουν για ήδη γνωστά σχήματα αγγείων (χύτρες με διάτρητα πώματα) και άλλοτε αναφέρει σπάνια ονόματα αγγείων (« φακός », « άρυστήρ », « βομβυλιός »), αλλά που τα συνδέει με συγκεκριμένες χρήσεις* επομένως, η λειτουργία που αποδίδεται στα αγγεία αυτά, μέσα από κείμενα χρονολογημένα με ακρίβεια, καθώς και η εξέταση του συνόλου όπου αναφέρονται, βοηθά ασφαλώς στον ακριβέστερο καθορισμό του σχήματος τους. Γίνεται προσπάθεια (...) να βρεθεί μια πλήρης απεικόνιση των όρων που χρησιμοποιούνται για την κεραμική της εποχής της Ιπποκρατικής Συλλογής. (shrink)

Responding to volatile criticisms frequently leveled at Leo Strauss and those he influenced, the prominent contributors to this volume demonstrate the profound influence that Strauss and his students have exerted on American liberal democracy and contemporary political thought. By stressing the enduring vitality of classic books and by articulating the theoretical and practical flaws of relativism and historicism, the contributors argue that Strauss and the Straussians have identified fundamental crises of modernity and liberal democracy.

On February 3, 2010, a “Letter of Concern from Bioethicists,” organized by fetaldex.org, was sent to report suspected violations of the ethics of human subjects research in the off-label use of dexamethasone during pregnancy by Dr. Maria New. Copies of this letter were submitted to the FDA Office of Pediatric Therapeutics, the Department of Health and Human Services Office for Human Research Protections, and three universities where Dr. New has held or holds appointments. We provide a critical appraisal of the (...) Letter of Concern and show that it makes false claims, misrepresents scientific publications and websites, fails to meet standards of evidence-based reasoning, makes undocumented claims, treats as settled matters what are, instead, ongoing controversies, offers “mere opinion” as a substitute for argument, and makes contradictory claims. The Letter of Concern is a case study in unethical transgressive bioethics. We call on fetaldex.org to withdraw the letter and for co-signatories to withdraw their approval of it. (shrink)

Rosamond Rhodes calls for a reconceptualization of research ethics and a fundamental shift in attitude toward both research subjects and scientific investigators. She recognizes the limits of the e...

This book is a collection of secondary essays on America's most important philosophic thinkers—statesmen, judges, writers, educators, and activists—from the colonial period to the present. Each essay is a comprehensive introduction to the thought of a noted American on the fundamental meaning of the American regime.

Laurence Ricard | : La notion d’autonomie personnelle joue un rôle central dans les théories politiques contemporaines et, plus spécifiquement, dans les théories de la justice. Or, dans le paradigme libéral dominant, elle est définie par une compréhension rationaliste de l’agent individuel. La présente étude défend la nécessité de redéfinir ce concept d’autonomie à la lumière des développements philosophiques et psychologiques qui ont complexifié notre compréhension de la subjectivité. L’emploi du concept d’autonomie relationnelle développé par certains auteurs féministes et (...) par certains théoriciens de la reconnaissance semble pour ce faire prometteur. Cet article cherche à montrer qu’une compréhension relationnelle de l’autonomie est nécessaire pour expliquer la motivation à la coopération sociale et pour redéfinir la justice et l’injustice de façon à ce qu’elles correspondent à l’expérience sociale vécue. | : The notion of personal autonomy plays a central role in contemporary political theories and especially in theories of justice. Generally speaking, the dominant liberal paradigm defines individual agency in a purely rationalistic manner. Against this tradition, the present study argues for the necessity of rethinking and redefining this rationalistic concept of autonomy in light of psychological and philosophical developments that have complicated our understanding of subjectivity. For this purpose, the concept of relational autonomy, developed by feminist authors and some theorists of recognition, is most promising. This article aims to show that a relational understanding of autonomy is necessary to explain motivations for social cooperation and to understand justice and injustice in a way that corresponds to lived social experience. (shrink)

Remnants of ancient retroviral infections during evolution litter all mammalian genomes. In modern humans, such endogenous retroviral (ERV) sequences comprise at least 8% of the genome. While ERVs and other types of transposable elements undoubtedly contribute to the genomic “junk yard”, functions for some ERV sequences have been demonstrated, with growing evidence that ERVs can be important players in gene regulatory processes. Here we focus on one particular large family of human ERVs, termed HERVH, which several recent studies suggest has (...) a key regulatory role in human pluripotent stem cells. Remarkably, this is not the first instance of an ERV controlling pluripotency. We speculate as to why this convergent evolution might have come about, suggesting that it may reflect selection on the virus to extend the time available for transposition. Alternatively it may reflect serendipity alone. (shrink)

Cette introduction invite à décadrer et à recadrer la thématique de l’effondrement, popularisée et médiatisée par la théorie dite « collapsologie », vers le plan des acteurs, des terrains, des temporalités, et des régimes d’énonciation. Nous appelons à documenter empiriquement ce que fait l’effondrement, et ce qu’en font celles et ceux à qui cette idée « fait » quelque chose. En effet, l’effondrisme pose la question des façons de se positionner non pas uniquement par rapport à une théorie, mais également (...) par rapport à des expériences individuelles et collectives. Le dossier vise à comprendre comment la réception de la « collapsologie » donne lieu à des jeux complexes entre désemparement et capacités d’agir. L’atterrissage sur un sol anthropocénique de plus en plus critique mérite une décisive discussion collective. L’hypothèse de cette majeure est que les expériences effondristes ont une valeur d’expérimentation à cet égard, notamment en créant un zone discursive et praxique où des cultures et des expériences politiques différentes sont amenées à se rencontrer et à collaborer. (shrink)

Les thèses défendues ici par l’un des membres du collectif Wu Ming prennent le contrepied des discours habituels tenus sur le populisme. Raconter des histoires, s’armer des pouvoirs propres du storytelling ne revient pas nécessairement à embobiner les masses dans des bobards : sous certaines conditions, cela peut au contraire aider à la circulation de récits émancipants, qui élèvent l’intelligence de ceux qui les racontent comme de ceux qui les écoutent.